Alysicarpus vaginalis (Common clover) : medicinal properties in alcoholic extraction

Alysicarpus vaginalis (Common clover) — family Fabacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The monograph draws on 19 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Whole plant. Documented pharmacological profile: Cisplatine-like.
   According to Rathi MA (2010): The Antiproliferative activity of AVEE with cisplatin, anticancer drug was studied using human ovarian cancer cells (PA-1) were measured by MTT assay. The presence of polyphenolic compound motivated us to evaluate the antioxidant & Antiproliferative potential. According to Sakle NS (2019): The present study intended to assess the anticancer potential of Alysicarpus vaginalis ethyl acetate fraction (AVEAF) in breast cancer cell lines (MCF-7 & MDA-MB-453) & against N-methyl-N-nitrosourea (MNU) induced mammary carcinoma in Sprague-Dawley rats which resemble the human estrogen dependent breast cancer.
2. Hepatitis, jaundice, cirrhosis, liver fibrosis : Plant part used: Aerial parts. Documented pharmacological profile: Silymarine-like.
   According to Rathi (2015): Rathi et al, Hepatoprotective activity of ethanolic extract of Alysicarpus vaginalis against nitrobenzene-induced hepatic damage in rats, South Indian J. The present study aimed to evaluate the hepatoprotective activity of ethanol extract of A. According to Bashir M (2018): It has been reported that these species possess analgesic, anti-inflammatory, antimicrobial, antiplasmodial, mosquitocidal, antioxidant, hepatoprotective, larvicidal, antiproliferative & antifertility activity.
3. Bacterial infection : Plant part used: Aerial parts.
   According to Rattanata N (2014): Antibacterial activity against Aeromonas hydrophila, Aeromonas caviae, Edwarsiella tarda, Plesiomonas shigelloides, Ralstonia spp., Xanthomonas campestris pv. Vesicatoria, Salmonella spp. According to Silva (2015): ternatea can function as a potent antibacterial agent against common food poising bacterial pathogen, B.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo from the Traditional Martinique Pharmacopoeia.