Annona glabra (Mamen) : medicinal properties in alcoholic extraction

Annona glabra (Mamen) — family Annonacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The monograph draws on 28 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Neurodegenerative disorders : Plant part used: Sheet.
2. Cancer : Plant part used: Seed. Documented pharmacological profile: Adriamycine-like.
   According to Cochrane CB (2008): However, extracts were highly cytotoxic to drug sensitive (CEM) & multidrug-resistant leukemia (CEM/VLB) cell lines. To validate the ethnopharmacological claims against cancer, the anticancer effects of alcoholic extracts prepared from pond apple leaves, pulp and seed, were investigated in human Leukemia cell lines. According to Dev A (2021): This review highlights anticancer effects of Annona species in cancer therapy, the efficacy of its bioactive components on diverse cancer types & their mechanism of action and also summarizes the use of these phytochemicals for the purpose of developing a promising anticancer drug candidate in future.
3. Pest control : Plant part used: Seed.
   According to Prijono D (1993): Jussieu) seed extracts against Phaedonia inclusa Stal (Coleoptera: Chrysomelidae) was evaluated in laboratory. Control leaves were dipped in water containing Tween 20 (0.2%) & ethanol (5%). According to Basana IR (1994): The insecticidal activity of each extract was tested in a leaf-residue bioassay.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Filo gèn' without modification (CC BY 2.0). License : CC BY 2.0.