Basella alba (Malabar spinach) : medicinal properties in alcoholic extraction

Basella alba (Malabar spinach) — family Basellacéess.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 19 indications in alcoholic extraction for this species. The monograph draws on 59 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Liver cirrhosis, hepatitis, fatty liver disease : Plant part used: Aerial_parts. Documented pharmacological profile: Silymarine-like.
   According to Nirmala A (2009): In liver, the changes caused after induction of diabetes was global microvesicular steatosis .The portal tracts appeared normal & central veins appeared congested, which was brought back to normal after feeding with BR. The diabetes-induced rats were fed with BR(400 mg/100 gm body weight orally through a gavage), when tested after ingestion the fasting blood glucose levels were remarkably reduced to normal & liver glycogen content was remarkably increased. According to Yanadaiah JP (2011): The present study was conducted to evaluate the hepatoprotective activity of aqueous ethanolic extract of aerial parts of BR in wistar rats.
2. Microbial infection caused by S. aureus, P. aeruginosa and E. coli : Plant part used: Aerial_parts.
   According to Oyewole OA (2012): The antimicrobial effects of ethanolic extract of Basella alba against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, & Candida albicans was determined using the agar cup plate method. aureus was 100mg/ml for the ethanolic extract of the leaf & stem of BA . According to Sushila R (2010): The minimum inhibitory concentration of methanolic extract was 6.25μg/ml against Staphylococcus aureus, Micrococcus luteus, Pseudomonas aeruginosa & Bacillus subtilus & 12.5μg/ml against Escherichia coli.
3. Memory impairment, adjunctive treatment for Alzheimer’s disease : Plant part used: Aerial_parts.
   According to Hou BY (2024): The amyloid-beta peptide (Aβ) is the neurotoxic component in senile plaques of Alzheimer's disease (AD) brains.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Sengai Podhuvan without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.