Brassica oleracea (Chou-Ponmé) : medicinal properties in alcoholic extraction

Brassica oleracea (Chou-Ponmé) — family Brassicacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 16 indications in alcoholic extraction for this species. The monograph draws on 61 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Liver disorders : Plant part used: Sheet. Mentioned synergistic association: Persea americana-huile fixe, Zingiber officinale-rhizome.
   According to Al-Howiriny T (n.d.): CCl 4 induced hepatotoxicity in all treated animals was evident by elevated serum GOT, GPT, ALP, GGT and bilirubin levels and simultaneous fall in NP-SH and increased MDA activities in liver tissue. The BO extract at the doses of 150 & 300 mg/kg produced significant hepatoprotection by decreasing the activity of serum enzymes, bilirubin, while it significantly increased the levels of NP-SH & decreased MDA of liver tissue. According to Ahmed MS (2013): increases in Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Alanine Phosphatase (ALP), Serum Bilirubin & decrease in Total proteins content, which were restored towards normalization in extracts treated rats.
2. Cancer : Plant part used: floret.
   According to Hashem SA (2012): When myrosinase hydrolysate was tested for cytotoxic activity on the colon cancer cell line it showed very high activity – 95% lethality up to 0.78 µg/mL. The crude extract (80% alcohol extract) of broccoli florets was examined for cytotoxic activity against different human cancer cell lines, it showed good inhibition of colon cancer (IC(50) 3.88 µg/mL). According to Lavanya B (2011): Brassica oleracea is extensively used as Anthelmintic, healing of peptic ulcers, slowing down growing cancer cells.
3. Type II diabetes mellitus : Plant part used: Sheet. Documented pharmacological profile: Metformine-like.
   According to Huchalah V (2008): In the present investigation its antidiabetic potency was tested on the serum insulin level in experimental diabetes in Wistar rats. There was significant increase in the serum insulin level compared to diabetic group (p<0.05). According to Assad T (2014): capitata (MEB) was evaluated in alloxan-induced diabetic rabbits.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by George Chernilevsky without modification (CC BY-SA 2.5). License : CC BY-SA 2.5.