Caesalpinia bonduc (Kannik-gri) : medicinal properties in alcoholic extraction

Caesalpinia bonduc (Kannik-gri) — family Caesalpiniacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The monograph draws on 61 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Fungal infection : Plant part used: Seed. Documented pharmacological profile: Itraconazole-like.
   According to SUBRAMANI V (2014): nigricans MTCC 613 (F2) whereas smaller effect was observed in Candida glabrata MTCC 3984 (F1). In fungi, this was effective against Epidermophyton floccosum var. According to Gadakh M (2009): The plant has been reported to possess antimalarial, antifungal, antioxidant, anticancer, antipyretic, antifertility antiviral & antimalarial etc.
2. Benign prostatic hyperplasia (BPH) : Plant part used: Seed. Documented pharmacological profile: Finastéride-like.
   According to Sasidharan S (2022): Benign prostatic hyperplasia (BPH) is a major chronic disease affecting men, & the therapeutic agents currently used to manage it have significant side effects. bonduc seed extracts treatment significantly decreased prostate weight & prostatic index in rats with TP-induced BPH.
3. Adjuvant treatment for ascites carcinoma : Plant part used: Seed.
   According to DEEPIKA KS. N (2014): The present study aims to evaluate the anticancer potential of ethanolic extract and its different fractions of Caesalpinia bonduc seeds against Ehrlich Ascites Carcinoma (EAC) cell lines. Conclusions: Petroleum ether fraction of ethanolic extract of C bonduc seeds has significant anticancer activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by David E Mead without modification (CC0 1.0). License : CC0 1.0.