Cinnamonum verum (Cinnamon) : medicinal properties in alcoholic extraction

Cinnamonum verum (Cinnamon) — family Lauracées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 20 indications in alcoholic extraction for this species. The monograph draws on 106 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Bark. Documented pharmacological profile: Amikacine-like.
   According to Sasidharan VK (1998): which are indigenously used in Kerala, India for curing various infections were tested against a fungus (Aspergillus niger) and gram positive and negative bacteria (Staphylococcus aureus & Escherichia coli, respectively). citratus has the highest antifungal activity while E. According to Salma L (2019): Evaluation of the in vitro antibacterial activity of the ethanolic extract isolated from Cinnamomum zeylanicum bark against two food borne pathogens, Gram-positive Staphylococcus aureus & Gram-negative Escherichia coli.
2. Fungal infection : Plant part used: Bark. Documented pharmacological profile: Chloramphénicol-like, Ciprofloxacine-like.
   According to Author (2012): The antifungal activity of barks of Cinnamomum Zeylanicum & leaves of Eucalyptus microtheca crude extracts were tested in vitro by agar well diffusion method against Penicillium digitatum & Aspergillus Niger fungi. Alcoholic (methanolic & ethanolic) & aqueous crude extracts were tested to evaluate for their antifungal activities. According to Matan N (2011): The antifungal activities of cinnamon oil, clove oil, anise oil & peppermint oil, & their main components (cinnamaldehyde, eugenol, trans-anethole, & menthol, respectively) against molds identified from areca palm leaf sheath (Mucor dimorphosporus, Penicillium sp, Aspergillus niger & Rhizopus sp.) were investigated.
3. Cancer : Plant part used: Bark. Documented pharmacological profile: Cisplatine-like.
   According to Westra WH (1998): Westra WH et al: Squamous cell carcinoma of the tongue associated with Cinnamon gum use: a case report. According to Varadarajan S (2020): Conclusion: CV its active compounds exhibited in vitro anticancer effects on oral squamous cell carcinoma. Presl extract & its active constituents, such as cinnamaldehyde, 4 hydroxycinnamic acid, & eugenol on oral squamous cell carcinoma cell line.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by David J. Stang without modification (CC BY-SA 4.0. License : CC BY-SA 4.0.