Cleome rutidosperma (White Mouzanmbé) : medicinal properties in alcoholic extraction

Cleome rutidosperma (White Mouzanmbé) — family Capparacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The monograph draws on 44 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Pain : Plant part used: Aerial parts. Documented pharmacological profile: Aspirine-like.
   According to Bose A (2007): Oral administration of the ethanolic extract (200 a&400 mg/kg, p.o) & its fractions (200 mg/kg each) of the aerial parts of Cleome rutidosperma produced significant analgesic activity in acetic acid-induced writhing & tail immersion tests, anti-inflammatory effect against carrageenin induced inflammation & adjuvant induced polyarthritis & antipyretic activity against yeast-induced pyrexia. According to Mondal (2009): Mondal et al, Analgesic, anti-inflammatory & antipyretic studies of Cleome rutidosperma DC.
2. Fungal infection : Plant part used: Aerial parts. Documented pharmacological profile: Clotrimazole-like.
   According to Knunta A (2011): The extracts were vacuum dried & studied for in vitro antifungal activity against Aspergillus niger, Penicillium notatum, Candida albicans, Helminthosporium solani. Clotrimazole (25 µg/ml) was used as reference control for antifungal studies. According to Morah F (2018): The oil exhibited antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus faecalis, Candida albicans & Aspergillus niger.
3. Osteoarthritis, rheumatism, oedema : Plant part used: Aerial parts. Documented pharmacological profile: Diclofénac-like.
   According to Bose A (2007): Oral administration of the ethanolic extract (200 a&400 mg/kg, p.o) & its fractions (200 mg/kg each) of the aerial parts of Cleome rutidosperma produced significant analgesic activity in acetic acid-induced writhing & tail immersion tests, anti-inflammatory effect against carrageenin induced inflammation & adjuvant induced polyarthritis & antipyretic activity against yeast-induced pyrexia. According to Mondal (2009): Mondal et al, Analgesic, anti-inflammatory & antipyretic studies of Cleome rutidosperma DC.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

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