Cnidoscolus chayamansa (Lachaya) : medicinal properties in alcoholic extraction

Cnidoscolus chayamansa (Lachaya) — family Euphorbiacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The monograph draws on 47 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: 5-Fluoro-Uracile-like.
   According to Pillai K (2012): The present investigation was carried out to evaluate the antitumor activity of Ethanolic extracts of CC in DLA tumor bearing mice. Plants used against cancer-an extension of the work of Jonathan Hartwell. According to Pillai K (2014): The present study was performed experimentally by Invitro method to examine the anti-cancer activity at various concentration (62.5μg/ml – 1000 μg/ml) of ethanolic extract of the leaves of Cnidoscolus chayamansa against HT-29 (Colon Carcinoma) cell lines using MTT assay method.
2. Arthritis, osteoarthritis, rheumatism : Plant part used: Sheet. Documented pharmacological profile: Indometacine-like.
   According to García-Rodríguez RV (2014): To determine the antiinflammatory activity, the TPA-induced mouse ear edema & the carrageenan-induced mouse paw edema assays were used. CC is also used as a traditional remedy for the treatment of diabetes, rheumatism, gastrointestinal disorders a& inflammation-related diseases. According to Onasanwo SA (2011): METHODS: The analgesic activity of the extract was assayed by the formalin-induced paw licking test, acetic acid-induced abdominal writhing & hot plate test, whereas its anti-inflammatory activity was determined by its effects on carrageenan-induced paw edema.
3. Hypercholesterolaemia, hypertriglyceridaemia, atherosclerosis : Plant part used: Sheet. Documented pharmacological profile: Atorvastatine-like.
   According to Olaniyan M (2017): Olaniyan M et al, Cholesterol lowering effect of Cnidoscolus aconitifolius leave extracts in egg yolk induced hypercholesterolemia in rabbit. According to Miranda-Velasquez L (2010): In an in vivo model, high-cholesterol diet administered to mice Balb/c induced hypercholesterolemia.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo from the Traditional Martinique Pharmacopoeia.