Conyza canadensis (Zèb-Kodenn) : medicinal properties in alcoholic extraction

Conyza canadensis (Zèb-Kodenn) — family Asteracées.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The monograph draws on 39 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Whole plant. Documented pharmacological profile: Imipenem-like, Streptomycine-like.
   According to TUGCE ONBAS (2017): coli,, Listeria monocytogenes, Pseudomonas aeruginosa, Salmonella enteritis, Staphylococcus aureus, Enterococcus faecalis. In this present study, the antimicrobial & antibiofilm activities of different extracts of Conyza canadensis-L (leaves) collected from Ankara (Turkey) & Rhododendron Ponticum-L (flowers), were evaluated against clinical isolated microorganisms as well as food borne such as Bacillus cereus, B. According to Veres K (2012): The antimicrobial activities of the oils were tested on Gram-positive (Enterococcus faecalis, Staphylococcus aureus & Streptococcus pyogenes), Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria, reference fungal strains & fungal strains isolated from patients (Candida, Cryptococcus, Trichophyton, Rhodotorula & Aspergillus) by agar disc diffusion and broth dilution methods.
2. Fungal infection : Plant part used: Whole plant. Documented pharmacological profile: Amphotericine-B-like, Miconazole-like.
   According to PHUONG NB (2015): albicans) & Trichosporon insectorum (T. Two fungal pathogens used to determine the bioactive activity of these extracts were Candida albicans (C. According to SHAKIRULLAH (2011): aureus, Trichophyton longifusus, C.
3. Memory problems, Alzheimer’s disease : Plant part used: Whole plant. Documented pharmacological profile: Donepezil-like.
   According to SHOEIB AM (2013): Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive and memory deterioration associated with shrinkage of brain tissue, with localized loss of neurons mainly in the hippocampus & basal forebrain, with central cholinergic loss neurotransmitter-acetylcholine and also reported to be associated with accumulation of β amyloïd plaques leading to oxidative stress and inflammation. The above results indicate memory enhancing capacity of the C canadensis ethanolic herbal extract.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Rasbak without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.