Corchorus olitorius (Jit) : medicinal properties in alcoholic extraction

Corchorus olitorius (Jit) — family Malvacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The monograph draws on 65 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Tamoxifène-like. Mentioned synergistic association: Amaranthus hybridus-feuille.
   According to Ismail EH (2018): An in vitro cytotoxic assay of the biocompatible Au NPs revealed a strong cytotoxic activity in three human cancer cell lines, namely, colon carcinoma HCT-116, hepatocellular carcinoma HepG-2, & breast adenocarcinoma MCF-7. According to Shariare MH (2021): In-vitro cancer cell line study data suggests that liposomal delivery of phytol was more active at lower concentration compared to pure phytol, for specific cell lines,. Phytol, a pharmacologically active compound present in Corchorus olitorius leaf exhibit a range of activity including anti-inflammatory, antioxidant, anticancer, hepatoprotective etc.
2. Type II diabetes mellitus : Plant part used: Sheet. Documented pharmacological profile: Glibenclamide-like.
   According to Egua OM (2013): The study was carried out using normoglycaemic, glucose challenged & alloxan induced diabetic albino rats. The ethanolic seed extract of Corchorus olitorius was studied to ascertain its possible antidiabetic effect. According to Olusanya AR (2018): Ethanolic extract of Corchorus olitorius leaf was investigated for antidiabetic activity in alloxan-induced diabetic rats.
3. Thrombosis : Plant part used: Sheet. Documented pharmacological profile: Héparine-like.
   According to Siccuan JA (n.d.): Thrombosis is the formation of blood clot in a vessel wall. After 12 hours of COE injection, 1 mg/kg of kappa-carrageenan dissolved in NSS was injected intravenously in the rat tail to promote thrombosis. According to Sharaf A (1969): Sharaf A et al, Pharmacological study of Corchorus olitorius L., seeds with special reference to its cardiovascular activity, Qualitas Plantarum et Materiae Vegetables, 17(4):305-312, 1969,.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Dinesh Valke without modification (CC BY-SA 2.0). License : CC BY-SA 2.0.