Costus spicatus (Kann Kongo) : medicinal properties in alcoholic extraction

Costus spicatus (Kann Kongo) — family Costacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The monograph draws on 20 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Type II diabetes mellitus : Plant part used: Rhizome. Documented pharmacological profile: Glibenclamide-like.
   According to Femi-Olabisi F (2021): Insulin resistance is the hall mark of PCOS as it predisposes the affected subjects to a higher risk of impaired glucose tolerance & type 2 diabetes mellitus (T2DM). Conclusion: These compounds can be explored as potential therapeutic agents for the management of insulin resistance in PCOS, subject to further experimental validation. According to Sivalungam MA (2019): ECS & Glibenclamide of STZ induced diabetic animals restored the normal plasma glucose levels & SGOT, SGPT & ALP levels without damaging the pancreas.
2. High blood pressure, fluid retention, oedema : Plant part used: Sheet. Documented pharmacological profile: Hydrochlorothiazide-like.
   According to Picanço LCDS (2016): Results: CSE significantly reduced the venom-induced edema & nociception at all concentrations tested & inhibited migration of inflammatory cells at the three least concentrations (5.0, 7.5 & 10 mg/kg/25 μl PBS). (Costaceae) is used by the Amazonian population to treat inflammation, pain and other pathological manifestations. According to Moreno KG.T (2021): We assessed whether ESCS has acute or prolonged diuretic activity.
3. Atherosclerosis : Plant part used: Sheet. Documented pharmacological profile: Rosuvastatine-like.
   According to Lorençone BR (2021): is a medicinal species frequently prescribed for the treatment of cardiovascular diseases. This study aims to evaluate the effects of this species against the development of atherosclerosis. According to Sivalungam AM (2021): Confirmed the effect diabetic medicinal plants in restore in pancreas of ECS in anti-hyperglycaemic activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Ben Cody without modification (CC BY 4.0). License : CC BY 4.0.