Cytrus hystrix (Kaffir lime) : medicinal properties in alcoholic extraction

Cytrus hystrix (Kaffir lime) — family Rutacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 13 indications in alcoholic extraction for this species. The monograph draws on 118 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Neuronal senescence : Plant part used: Fruit.
   According to Pattarachotanant N (2020): The extracts protected neuronal senescence by inhibiting ROS generation. Collectively, CH extracts could protect high glucose-induced human neuronal senescence by inducing cell cycle progression & up-regulation of SIRT1, thus leading to the improvement of the neuronal cell functions. According to Okta M (2018): Intrinsic aging is caused by genetic factors & increasing age.
2. Urolithiasis, gout attack : Plant part used: Sheet. Documented pharmacological profile: Allopurinol-like.
3. Doxorubicin-induced liver and heart disease : Plant part used: Fruit.
   According to Pallavi M (2021): Remarkably, lime peel extract followed by sour orange & orange at 500 mg kg-1 dose improved hepatic architecture to near normal with less deposition of fat globules & fewer sinusoids. According to Arumugam A (2015): maxima leaf extracts possess hepatoprotective action against paracetamol induced hepatotoxicity. The leaf extracts restored the liver function markers & hepatic antioxidants to the normal level than elevated levels noticed on paracetamol control at p < 0.001.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Katja Schulz without modification. License : (Flickr).