Delonix regia (Flanbwayan) : medicinal properties in alcoholic extraction

Delonix regia (Flanbwayan) — family Caesalpiniacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 26 indications in alcoholic extraction for this species. The monograph draws on 55 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Flower. Documented pharmacological profile: Tamoxifène-like.
   According to PUSAPATI MADAN RANJIT (2014): The cytotoxic property of the extract was determined by using MTT assay against Breast cancer (MCF-7), cervix (HeLa), Brain & colon cancer cells. The cytotoxic activity of the extract showed, IC50 concentrations (μg/ml) against MCF-7 (Breast), Carcinoma of cervix HeLa cells, Carcinoma of the Brain, and Carcinoma of colon Cells against Tamoxifen are 141.6 ± 0.08, 223.7 ± 2.16, 173.9 ± 0.7, 168.33 ± 0.04 respectively. According to Abou-Zeid AH (2023): Biologically, in vitro anticancer activity against four human tumor cell lines, in vivo hepatoprotective activity against CCl4-induced liver injury, & in vivo antioxidant activity was studied.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Acide ascorbique-like.
   According to Thomas B (2021): Antioxidant activity was assessed by radical scavenging & reduction assays. regia flowers were evaluated for their antioxidant, antidiabetic, anti-inflammatory & cytotoxic activity to justify its use as a medicinal plant. According to Author (2016): Antioxidant lutein is a fat-soluble xanthophyll and could be found in a wide range of natural sources.
3. Osteoarthritis, arthritis, oedema, rheumatism, multiple sclerosis : Plant part used: Sheet. Documented pharmacological profile: Indometacine-like.
   According to Vaishāli (2012): The antiinflammatory activity was studied using carrageenan-induced rat paw edema & cotton pellet granuloma at three different doses (100, 200, & 400 mg/kg b.w. The ethanol extract of D regia leaves was exhibited significant antiinflammatory activity at the dose of 400 mg/kg in both models when compared with control group. According to Shewale V D (2012): The anti-inflammatory activity was studied using carrageenan-induced rat paw edema & cotton pellet granuloma at three different doses (100, 200, & 400 mg/kg b.w.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Dinkun Chen without modification (CC BY 4.0). License : CC BY 4.0.