Dioscorea alata (Yanm Sen-marten) : medicinal properties in alcoholic extraction

Dioscorea alata (Yanm Sen-marten) — family Dioscoréacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 4 indications in alcoholic extraction for this species. The monograph draws on 72 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Type II diabetes mellitus : Plant part used: Tuber. Documented pharmacological profile: Metformine-like.
   According to Maithili V (2011): To evaluate the antidiabetic activity of ethanolic extract of Dioscorea alata in glucose loaded & alloxan induced diabetic rats. Diabetes mellitus was induced by alloxan monohydrate (120 mg/kg, i.p.) in physiological saline after overnight fasting for 18 hours. According to Guo X (2015): Peel extract exerted better bioactivity than flesh extract, which indicated that purple yam peel, a kind of kitchen waste that is always overlooked, might serve as a promising therapeutic natural product for the prevention of diabetes or other advanced glycation end products-related diseases.
2. Doxorubicin-induced cardiomyopathy : Plant part used: Tuber.
   According to Chen CT (2017): The present study was designed to explore whether yam could protect the heart from doxorubicin (DOX)-induced oxidative stress leading to cardiotoxicity in vivo. purpurea, against DOX-induced cardiotoxicity in experimental mice were evaluated.
3. Osteoporosis : Plant part used: Tuber.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Forest & Kim Starr without modification (CC BY 4.0). License : CC BY 4.0.