Dissotis rotundifolia (Lyenn-violèt-savann) : medicinal properties in alcoholic extraction

Dissotis rotundifolia (Lyenn-violèt-savann) — family Melastomacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 33 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Gentamycine-like.
   According to Abere TA (2010): Inhibitory activity against clinical strains of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus & Salmonella typhi were compared with Gentamycin. typhi to varying extents. According to Usanga VU (2023): Antimicrobial test was assessed by agar diffusion at various concentrations against five clinical isolates namely; Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Citrobacter freundii & Candida species.
2. Fever, pain, hyperalgesia : Plant part used: Whole plant. Documented pharmacological profile: Aspirine-like.
   According to Roko GO (2020): The aim of this study is to evaluate the anti-inflammatory, analgesic & antipyretic properties of ethanolic extracts of these plants. Analgesic activity was assessed by the pain method induced by 3% acetic acid & the tail immersion method with Wistar rats.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Whole plant. Documented pharmacological profile: Diclofénac-like.
   According to Kofi Yeboah O (2021): The leaf extract of DR showed significant amelioration of acetic acid- induced ulcerative colitis which may be attributable to its anti-inflammatory effect. 30 & 300 mg kg-1 of the extract significantly (P < 0.0001) inhibited weight loss & colon oedema. According to Roko GO (2020): Results: After injection of formalin to animals, inflammatory reaction was almost immediate with appearance of classic signs of acute local inflammation (Redness, pain, heat & edema) at the five experimental groups.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Nativeplants garden without modification (CC BY 4.0). License : CC BY 4.0.