Dunaliella salina (Red algae) : medicinal properties in alcoholic extraction

Dunaliella salina (Red algae) — family Dunalielliacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The monograph draws on 96 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Whole plant. Mentioned synergistic association: Taxol.
   According to Elleuch F (2020): The biological activity assessment was performed on the Triple Negative Breast Cancer (TNBC) using 4T1 murine cells as a model. isolated from the Tunisian coastal zone possesses any anticancer activity. According to Nagasawa H (1989): Moreover, mammary gland susceptibility to mammotrophic hormones was affected little by Dunaliella.
2. Type II diabetes mellitus : Plant part used: Whole plant. Documented pharmacological profile: Glibenclamide-like.
   According to El-Baz FK (2016): The aim of the present investigation is to study the protective effect of the Dunaliella salina extract against streptozotocin (STZ)- induced type 2 diabetes mellitus (T2DM) in male rats. The biological effect of DS could be attributed to its high level of 9-cis – carotene which protect cells from the oxidative stress, hence, treatment of diabetic rats with DS extract declared therapeutic potential in hyperglycemia dominance which need further clinical trial for usage as nutraceutical product, in diabetic regimen,. According to El-Baz FK (2016): The aim of the current research is to study the effect of Dunaliella salina ethanolic extract on renal function & inflammatory cytokines in streptozotocin (STZ)-induced diabetic rats.
3. Bacterial infection : Plant part used: Whole plant.
   According to Herrero M (2006): In the present work, the antimicrobial activity of different pressurized liquid extracts obtained from Dunaliella salina microalga was tested against several microorganisms of importance for the food industry (Escherichia coli, Staphylococcus aureus, Candida albicans, & Aspergillus niger). Because the main antimicrobial activity of the extracts was against bacteria, the extracts can be considered to be specifically antibacterial. According to Herrero M (2006): In the present work, the antimicrobial activity of different pressurized liquid extracts obtained from Dunaliella salina microalga was tested against several microorganisms of importance for the food industry (Escherichia coli, Staphylococcus aureus, Candida albicans, & Aspergillus niger).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Angu without modification (CC BY 4.0). License : CC BY 4.0.