Eclipta alba (Podjak) : medicinal properties in alcoholic extraction

Eclipta alba (Podjak) — family Astéracées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 31 indications in alcoholic extraction for this species. The monograph draws on 153 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Aerial parts. Documented pharmacological profile: 5-Fluoro-Uracile-like.
   According to Kumar K (2013): Kumar K et al, Hepatoprotective effect of Eclipta Alba on experimentally induced liver damage in rats. According to Prabhu K (2011): Prabhu K et al, Hepatoprotective effect of Eclipta Alba on paracetamol induced liver toxicity in rats.
2. Liver disease : Plant part used: Whole plant. Documented pharmacological profile: Silymarine-like. Mentioned synergistic association: association synergique avec MELIA AZEDARACH-L (Feuille), Piper longum-semence.
   According to Kumar K (2013): Kumar K et al, Hepatoprotective effect of Eclipta Alba on experimentally induced liver damage in rats. According to Prabhu K (2011): Prabhu K et al, Hepatoprotective effect of Eclipta Alba on paracetamol induced liver toxicity in rats.
3. Bacterial infection : Plant part used: Aerial parts. Documented pharmacological profile: Ciprofloxacine-like.
   According to Karthikkumar S (2007): the hexane, ethyl acetate, ethanol & water extract of aerial parts of the Eclipta prostrata were tested for its antibacterial activities against Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae, Salmonella typhi, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. Highest activity of both antibacterial & antioxidant was observed only in ethanol & ethyl acetate extracts, while hexane & water extracts did not show any significant results. According to Uddin N (2010): Large zone of inhibition was observed in disc diffusion Antibacterial screening against gram negative Salmonella typhi, Shigella sonnei, Escherichia coli, Salmonella paratyphi, Pseudomonas sp (1) & Pseudomonas sp (II), & gram-positive Bacillus subtilis, Bacillus Cereus, Bacillus megaterim & Staphylococcus aureus at the concentration of 1mg/disc.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by J.M. Garg without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.