Elephantopus mollis (Rabbit-ear) : medicinal properties in alcoholic extraction

Elephantopus mollis (Rabbit-ear) — family Astéracées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 21 indications in alcoholic extraction for this species. The monograph draws on 92 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Paclitaxel-like.
   According to Bich Ngoc TT (2020): Previous studies reported that crude extracts of this plant could inhibit several cancer cell lines, including breast carcinoma MCF-7, liver carcinoma HepG2, colorectal carcinoma DLD-1, lung carcinoma NCI–H23, etc. Aim: In this study, the anticancer activity & associated molecular mechanism of EM which is distributed in Vietnam were investigated. According to Chan CK (2016): In conclusion, our data showed that DET induced apoptosis & cell cycle arrest in HCT116 colorectal carcinoma, suggesting that DET has potential as an anticancer agent for colorectal carcinoma.
2. Bacterial infection : Plant part used: Sheet.
   According to Anitha VT (2012): Aqueous, acetone, benzene, chloroform, ethanol, & petroleum ether extracts were prepared from powdered materials were used for preliminary phytochemical & antimicrobial studies using standard methods. To examine the ethanol, aqueous, chloroform, benzene, acetone & petroleum ether extracts of, Hemigraphis colorata leaves & stem & Elephantopus scaber leaves, root & flower for the presence of phytoconstituents & screened the antibacterial activity against the selected pathogens. According to Hiradeve SM (2015): Hiradeve SM et al, Antibacterial & antifungal activities of Elephantopus scaber Linn.
3. Bone fracture : Plant part used: Aerial parts.
   According to Ngueguim FT (2012): Ethanolic extract of the leaves & twigs of Elephantopus mollis (EM) & whole plant of Spilanthes africana (SA) dose-dependently stimulated bone regeneration at the drill hole site. Conclusion: Ethanolic extracts of EM & SA accelerate fracture repair in rats via stimulatory effects on osteoblast differentiation & mineralization, thereby justifying their traditional use. According to SINGH SDJ (2002): scaber promoted Wound-healing activity in all the three Wound models.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Keisotyo without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.