Evolvulus alsinoides (Bléyè) : medicinal properties in alcoholic extraction

Evolvulus alsinoides (Bléyè) — family Convolvulacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 57 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Memory disorders, adjunctive treatment for Alzheimer’s disease : Plant part used: Aerial parts. Documented pharmacological profile: Piracetam-like. Mentioned synergistic association: Clitoria ternatea-parties aériennes, mangiferine, Ocimum tenuiflorum-feuille.
   According to Kumar S (2016): To investigate the effect of Polyherbal Formulation on cholinergic dysfunction in STZ induced Alzheimer’s disease (AD). Results: The study showed that STZ significantly impaired learning & memory with a significant enhancement in brain AChE, TBARS & reduction in brain GSH, Catalase & SOD levels. According to Nahata A (2009): The ethanol extract of EA & its ethyl acetate & aqueous fractions was evaluated for their memory enhancing properties.
2. Memory disorders : Plant part used: Whole plant. Documented pharmacological profile: Donepezil-like. Mentioned synergistic association: Bacopa monnieri, Tinospora cordifolia-plante entières.
   According to Kumar S (2016): To investigate the effect of Polyherbal Formulation on cholinergic dysfunction in STZ induced Alzheimer’s disease (AD). Results: The study showed that STZ significantly impaired learning & memory with a significant enhancement in brain AChE, TBARS & reduction in brain GSH, Catalase & SOD levels. According to Singh H (2009): the anti-amnesic potential of the aqueous extract obtained from Evolvulus alsinoides was determined in Alzheimer’s type of dementia induced mice.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Whole plant. Documented pharmacological profile: Indometacine-like.
   According to LEKSHMI UMD (2011): The pharmacological result showed that the ethanolic extract at a dose of 250 mg/kg body weight & 500 mg/kg body weight caused a significant (P < 0.05) inhibition of the carrageenan-induced rat paw oedema & a significant (P < 0.05) reduction of hyperpyrexia induced by Brewer’s yeast in rats. (Convolvulaceae) was investigated for anti-inflammatory, antipyretic & antidiarrhoeal properties in female albino rats. According to Reddy PA (2013): The chloroform & Ethyl acetate extracts of the plant have significant anti-inflammatory activity by both methods that is carrageenan & formalin induced paw oedema in rats at 200 & 400mg/kg body weight.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vengolis without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.