Hibiscus rosa (Gwo-Kokliko) : medicinal properties in alcoholic extraction

Hibiscus rosa (Gwo-Kokliko) — family Malvacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 26 indications in alcoholic extraction for this species. The monograph draws on 52 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Flower. Documented pharmacological profile: Chlorambucil-like.
   Selon Rasul HO (2023) : One of the most common malignancies diagnosed & the leading cause of death for cancer-stricken women globally is breast cancer. By using Lipinski's rule of five to the chosen compounds, the ADMET profile & drug-likeness characteristics were further examined to assess the anti-breast cancer activity.
2. Rheumatism, arthritis, osteoarthritis, oedema : Plant part used: Flower. Documented pharmacological profile: Diclofenac-like.
   Selon Birari RB (2009) : The anti-inflammatory activity of ethanolic extract of H rosa sinensis was evaluated using carrageenin induce paw edema, cotton pellet induces granuloma & xylene induce mice ear edema. The present study was undertaken to investigate the anti-inflammatory, analgesic & anti-pyretic activities of ethanolic extract of the flowers of Hibiscus rosa sinensis. Selon Begum Z (1927) : The oral administration of Hibiscus extract respectively has been shown significant (p<0.05) dose dependent analgesic (prolongation of the reaction time) & anti-inflammatory (inhibition of edema) effects at all the treated & standard groups when compared with the control group.
3. Pain, hyperalgesia : Plant part used: Root. Documented pharmacological profile: Diclofenac-like.
   Selon Birari RB (2009) : The present study was undertaken to investigate the anti-inflammatory, analgesic & anti-pyretic activities of ethanolic extract of the flowers of Hibiscus rosa sinensis. The result showed the plant has significant anti-inflammatory, analgesic and anti-pyretic effect. Selon Begum Z (1927) : The current study aimed to evaluate the analgesic & anti-inflammatory effects of the ethanolic extract of roots of Hibiscus rosa sinensis (HRS).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo from the Traditional Martinique Pharmacopoeia.