Hura crepitans (Hourglass) : medicinal properties in alcoholic extraction

Hura crepitans (Hourglass) — family Euphorbiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The monograph draws on 40 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Type II diabetes mellitus : Plant part used: Seed. Documented pharmacological profile: Metformine-like.
   Selon HALIMAT LY (2024) : Likewise, the extract increased serum &pancreatic insulin levels, & signicantly ameliorated neuronal oxidative stress & inammation by reducing the expression levels of cholinesterase, NF-κB, & COX-2 in the brain of hyperglycemic rats. This study evaluated the antidiabetic potential of methanolic extract of Hura crepitans using in vitro, in vivo, & in silico approach. Selon Igwenyi T (2017) : The study investigated the antidiabetic & hepatoprotective effects of ethanol extract of HC seed in alloxan-induced diabetic rats so as to ascertain its therapeutic value, safety & possible toxicity.
2. Hepatitis, cirrhosis, fatty liver disease : Plant part used: Seed.
   Os (2020) : Their protective effects were enunciated using animal models. This paper reviews the potential of the Hura crepitans plant in protecting the liver against drug-induced toxicity. Selon Owojuyigbe OS (2021) : Materials & methods The protective activities of ethanolic extract of HC stem bark was evaluated in CCl4-induced subacute liver damage in rats (1:1 v/v in olive oil, intraperitoneally (i.p.), twice weekly for 8 weeks).
3. Viraemia : Plant part used: Stem bark.
   Selon Taborda NA (2007) : Four extracts were prepared using hexane, ethyl acetate, methanol & water; the antiviral activity was tested against Vesicular Stomatitis Virus (VSV), serotypes Indiana & New Jersey & Bovine Herpes Virus (type 1 Bogotá strain). These results suggest that this extract contains antiviral compounds. Selon Auteur (s.d.) : Antimicrobial, Anti-inflammatory, Antiproliferative, Antioxidant,.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

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