Ixora coccinea (Ixora) : medicinal properties in alcoholic extraction

Ixora coccinea (Ixora) — family Rubiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 17 indications in alcoholic extraction for this species. The monograph draws on 102 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Fungal infection : Plant part used: Root. Documented pharmacological profile: Griséofulvine-like.
   Selon Davendran A (2020) : It act as a cure for various ailments like hepatic disorder, cancer, microbial infection, inflammatory etc. Pharmacological studies of this plant show that, it possesses antioxidant, antibacterial, gastro protective, hepato protective, anti-diarrhoeal, anti-nociceptive, anti-mutagenic & chemo preventive effects. Selon Okhale SE (2018) : This study aimed to investigate the chemical constituents & antimicrobial activity of the leaf Essential Oil (EO) of IC grown in Nigeria.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Acide ascorbique-like, Quercétine-like.
   Selon Aboudouiatif D (2013) : Oxidative stress, specifically lipid peroxidation, contributes to the pathogenesis of asthma. These facts led us to examine their antioxidant activities. Selon Bala NN (2011) : Among all the three extracts, methanolic extract have shown better scavenging & antioxidant property compared to other extracts in all the assay methods evaluated thereby leading it into the modern system of medicine in future.
3. Anxiety, insomnia, nervousness : Plant part used: Whole plant. Documented pharmacological profile: Diazépam-like.
   Selon Shan P Mohammed (2014) : The objective of this study was to evaluate the anxiolytic activity of Ixora coccinea ethanolic extract. The ethanolic extract ICEE shows a significant (P<0.01) anxiolytic effect during the elevated plus maze test & the hole board test in a dose dependent manner when compared with the standard dose of diazepam.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Pratheepps without modification (CC BY 4.0). License : CC BY 4.0.