Justicia gendarussa (Djapanna-nwè) : medicinal properties in alcoholic extraction

Justicia gendarussa (Djapanna-nwè) — family Acanthacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 16 indications in alcoholic extraction for this species. The monograph draws on 69 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: 5-Fluoro-Uracile-like.
   Selon Alarmal Mangaï S (2017) : The Chloroform, ethyl acetate & ethanol extract of the plant were used to analyse the cytotoxicity against the human cancer cell lines –human liver carcinoma cancer cell line (HepG2) & cervical cancer cell line (HeLa) by MTT assay. India has about several thousand medicinal plants which possess notable cancer curing properties. Selon Zain NC (s.d.) : Zain NC et al, EFFECT of 70% ETANOL EXTRACT Justicia gendarussa Burm.f, in CAPSULE to RENAL FUNCTION, LIVER FUNCTION, & LIPID PROFILE to SERUM for NORMAL ADULT MEN, Penulis : Rev Kurniati Septanti.
2. Arthritis, osteoarthritis, arthritis, rheumatism : Plant part used: Aerial parts. Documented pharmacological profile: Aceclofenac-like.
   Selon Jothimanivannan C (2010) : The anti-inflammatory activity of the extract was evaluated by using carrageenan-induced rat paw edema & cotton pellet granuloma method. The aim of the present study was to evaluate the anti-inflammatory & analgesic activities of the ethanol extract of aerial parts of Justicia gendarussa (EJG) in animal models. Selon Kumar K (2018) : In vitro studies revealed that pretreatment of ox-LDL induced hPBMCs with apigenin (25 μM) significantly (P < 0.05) reduced the levels of TLR4, MyD88, TRIF, TRAF6, NF-κB, COX-2, PGE2, IL-1β & TNF-α responsible for generating inflammation & elevated the level of anti-inflammatory cytokine, IL-10.
3. HIV : Plant part used: Sheet. Documented pharmacological profile: Lamivudine-like.
   Selon Auteur (2011) : Herbal cure: Justicia gendarussa: water willow prevents human influenza, Indiaheals.blogspot.in/2011/in/Justicia gendarussa-water-willow.html. Selon Sugumaran P (2013) : The obtained biomass of leaves, stem & root were examined for antibacterial activity against various human pathogenic organisms such as Staphylococcus aureus, Escherichia coli, Shigella sp., Pseudomonas sp. Rooting & biomass production of Justicia gendarussa has been achieved through a hydroponic system of cultivation.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vinayaraj without modification (CC BY 4.0). License : CC BY 4.0.