Lepidium sativum (Watercress) : medicinal properties in alcoholic extraction

Lepidium sativum (Watercress) — family Brassicacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The monograph draws on 70 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Liver disorders : Plant part used: Seed. Documented pharmacological profile: Silymarine-like.
   Selon Ahmed TE (2022) : Besides, the T2 group liver sections of mice were showed better effect of HMSELS on restoring the damaged liver histopathology almost toward normal. Conclusion: The HMSELS at a dose of 400 mg/kg/day (T2) was more effective on the liver function tests & liver histopathology that altered by feeding deep-fried palm oil diet. Selon Abdul-Malek HA (2021) : Aim of the study: In this study, we investigated the beneficial effect of LS ethanol & aqueous seed extracts on obesity, oxidative, inflammatory, & insulin sensitivity changes in the liver tissue of high fat diet (HFD)-fed rats.
2. Type II diabetes mellitus : Plant part used: Seed. Documented pharmacological profile: Insuline-like.
   Selon Shukla P (2012) : Antidiabetic profile of LSTA (50, 150 & 250 mg kg-1, i.p.) was assessed on alloxan induced diabetic rats upon 21 days continuous treatment. The present study aimed at investigation of antidiabetic efficacy of L. Selon Eddouks M (2005) : aqueous extract in normal & diabetic rats.
3. Hypothyroidism : Plant part used: Seed. Documented pharmacological profile: Levothyroxine-like.
   Selon Sharfeldeen Osman R (2018) : The current medical therapies for hypothyroidism are often deemed inadequate because of difficulties in regulating the level of thyroid hormones through use of conventional drugs. Hypothyroidism is a condition in which the thyroid gland does not produce enough thyroid hormones [triiodothyronine (T3) & thyroxine (T4)] which is commonly caused by iodine deficiency. Selon Hajomer R (2018) : Hypothyroidism is a condition in which the thyroid gland does not produce enough thyroid hormones (Triiodothyronine T3 & Thyroxine T4) which are commonly caused by iodine deficiency.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Salicyna without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.