Luffa acutangula (Tòchon) : medicinal properties in alcoholic extraction

Luffa acutangula (Tòchon) — family Cucurbitacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 87 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Fruit. Documented pharmacological profile: Cisplatine-like.
   Selon Dashora N (2015) : Dashora N et al, In vitro antioxidant & in vivo anti-tumor activity of Luffa acutangula against Dalton’s Lymphoma Ascites (DLA) cells bearing mice. Selon Dashora N (2015) : The objective of the present study is to explore the anticancer activity of the ethanolic & aqueous extracts of the Luffa acutangula in Swiss albino mice against Ehrlich Ascites Carcinoma (EAC) cell line. After 24 h of the last dose & then eighteen hours of fasting, the mice were sacrificed & antitumor effect of ETOH & aqueous extracts was assessed by evaluating tumor volume, viable & nonviable tumor cell count, tumor weight & hematological parameters of EAC bearing host.
2. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Seed. Documented pharmacological profile: Diclofénac-like.
   Selon Gill NS (2011) : amara ethanolic seed extract for antioxidant activity by 1,1-Diphenyl-2-picryl hydrazyl & Hydrogen peroxide method, anti-inflammatory by Carrageenan induced rat paw edema method & analgesic activity by tail flick and tail immersion methods. The above results concludes that ethanolic seed extract of L acutangula can be used as natural antioxidant, inflammation & in the treatment of pain. Selon Iyyamperumal U (2013) : Methods: Anti-inflammatory effect was evaluated by carrageenan induced hind paw edema & cotton pellet granuloma models.
3. Pain, hyperalgesia : Plant part used: Seed. Documented pharmacological profile: Pentazocine-like.
   Selon Singh Gill N (2011) : Singh Gill N et al, Evaluation of Antioxidant, Anti-Inflammatory & Analgesic Potential of Luffa acutangula Roxb. Selon Gill NS (2011) : The above results concludes that ethanolic seed extract of L acutangula can be used as natural antioxidant, inflammation & in the treatment of pain. amara ethanolic seed extract for antioxidant activity by 1,1-Diphenyl-2-picryl hydrazyl & Hydrogen peroxide method, anti-inflammatory by Carrageenan induced rat paw edema method & analgesic activity by tail flick and tail immersion methods.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Akaporn Bhothisuwan without modification (CC BY-SA 2.0). License : CC BY-SA 2.0.