Luffa cylindrica (Lyenn dishcloth) : medicinal properties in alcoholic extraction

Luffa cylindrica (Lyenn dishcloth) — family Cucurbitacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The monograph draws on 110 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Pain, hyperalgesia : Plant part used: Fruit. Documented pharmacological profile: Diclofénac-like.
   Selon Ali Esmail Al Snafi (2019) : The pharmacological investigation showed that LC possessed antiinflammatory, analgesic, antipyretic, hypoglycemic, antibacterial, antifungal, antiviral, anthelmintic, antioxidant, anticancer, hepatoprotective, antiemetic, wound healing, immunological, bronchodilating, reproductive effect & in treatment of cataract. Luffa cylindrica was used traditionally for the treatment of asthma, intestinal worms, sinusitis, chronic bronchitis pain, carbuncles, abscesses, inflammation, heat rashes of children in summer, bowels or bladder hemorrhage, hemorrhoids, jaundice, menorrhagia, haematuria, leprosy, spleenopathy, as anthelmintic, carminative, emmenagogue, galactagogue & as antiseptic. Selon Khan K.W (2013) : Ethanol extracts of leaves, male flowers & fruit peel of Luffa cylindrica (L.) Roem., were evaluated for analgesic effect using analgesy meter test, a mechanically induced pain model.
2. Bacterial infection : Plant part used: Fruit. Documented pharmacological profile: Ciprofloxacine-like.
   Selon Onegbule FA (2018) : In the antimicrobial evaluation, the ethanol & ethyl acetate extracts showed moderate antibacterial activity against Staphylococcus aureus, Salmonella typhi, & Bacillus subtilis. The ethyl acetate extract exhibited considerable antimicrobial activity against the test isolates compared to the ethanol extract. Selon Ahmad B (2013) : cylindrical exhibited good (64%) & crude methanolic extract, moderate (58%) antibacterial activity against Bacillus subtilis.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Male flower. Documented pharmacological profile: Indométacine-like.
   Selon Khan K.W (2013) : Ethanol & hexane extracts of the leaves & male flowers of Luffa cylindrica were evaluated for antiemetic & anti-inflammatory effect using chick emesis model & carrageenan induced rat paw oedema. Chlorpromazine 150 mg/kg & indomethacin 10 mg/kg orally were used as standard antiemetic & anti-inflammatory drugs . Selon —Abirami MS (2011) : The anti-inflammatory activity was evaluated using carrageenan-induced rat paw edema method in rats.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Dinesh Valke without modification (CC BY 4.0). License : CC BY 4.0.