Ocimum tenuiflorum (Tulsi) : medicinal properties in alcoholic extraction

Ocimum tenuiflorum (Tulsi) — family Lamiacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 33 indications in alcoholic extraction for this species. The monograph draws on 110 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Mentioned synergistic association: Azadirachta Indica-feuille.
   Selon Kamyab AA (2013) : Recently its efficacy against inflammatory response, hepatic injury & gastric ulcer has been elucidated in animal studies. In gastric epithelial tissue different derivatives of OS had anti-ulcer & anti-secretory characteristics & could heal gastric ulceration. Selon Magesh V (2009) : Therefore, the antitumor mechanism of ethanol extracts of Ocimum sanctum (EEOS) was elucidated in A549 cells in vitro & the Lewis lung Carcinoma (LLC) animal model.
2. Fungal infection : Plant part used: Sheet. Documented pharmacological profile: Fluconazole-like.
   Selon SHARMA A (2024) : In the present study, antidiabetic medicinal plants were screened for antifungal activity against Absidia Blakesleeana, a fungus causing mucormycosis (the black fungus). Fluconazole antibiotic was used as positive control. Selon Neha N (2020) : The antimicrobial activities of the plant against a wide variety of gram-positive & gram-negative bacteria, fungal & viral pathogens indicate that different extracts of this plant possess versatile anti-infective properties.
3. Depression : Plant part used: Whole plant. Documented pharmacological profile: Sertraline-like. Mentioned synergistic association: Nyctanthes arbortristis-feuille.
   Selon Pemminati S (s.d.) : Depression is a widespread Psychiatric disorder affecting around 5% of the population. In the traditional systems of medicine, many plants and formulations have been used to treat depression for thousands of years. Selon Sumina S (2022) : Aim: To evaluate the antidepressant activity of ethanolic leaf extract of Ocimum sanctum after subacute administration.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vinayaraj without modification (CC BY 4.0). License : CC BY 4.0.