Parthenium hysterophorus (Matritjè) : medicinal properties in alcoholic extraction

Parthenium hysterophorus (Matritjè) — family Asteracées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 15 indications in alcoholic extraction for this species. The monograph draws on 120 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Azithromycine-like, Cepaxime-like.
   Selon Fazal H (2011) : The extracts were tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Bacillus subtilis, Enterococcus spp., & Staphylococcus aureus by using agar well diffusion method. In the present study the, In-vitro antibacterial activity of 3 medicinal plants viz., Parthenium hysterophorus, Stevia rebaudiana & Ginkgo biloba were evaluated by using different solvent extracts. Selon -Sharif N (2021) : Variable results of antimicrobial activity against, Salmonella paratyphi A, Pseudomonas aeruginosa, Proteus mirabilis & Escherichia coli were obtained.
2. Cancer : Plant part used: Sheet. Documented pharmacological profile: Adriamycine-like. Mentioned synergistic association: Hedyotis corymbosa.
   Selon Pandey K (2012) : To study the anticancer activity of ethanolic extract of leaves of Parthenium hysterophorus & Oldenlandia corymbosa by SRB assay method on K562 human leukemia cancer cell line. Results: P hysterophorus & O corymbosa showed significant anticancer activity on K562 human leukemia cancer cell line. Selon Kumar S (2013) : Ethanol fraction showed noticeable cytotoxic activity (81-85%) in SRB assay against MCF-7 & THP-1 cancer cell lines at 100 μg/ml concentration, while lower activity was observed with DU-145 cell line.
3. Oxidative stress : Plant part used: Root. Documented pharmacological profile: acide ascorbique-like.
   Selon Kaur M (2020) : It can stimulate numerous cellular & immune responses that may translate into Oxidative stress, allergies, and inflammation. The effect of PH flower extract was evaluated on cell viability, oxidative stress & inflammation in A549 lung cancer cell line by spectrophotometric & reverse transcriptase-polymerase chain reaction methods. Selon Kumar S (2013) : Reducing power & hydroxyl radical scavenging activity assays were used to measure antioxidant activity.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Apurv013 without modification (CC0 1.0). License : CC0 1.0.