Petiveria alliacea (Arada) : medicinal properties in alcoholic extraction

Petiveria alliacea (Arada) — family Phytolaccacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 12 indications in alcoholic extraction for this species. The monograph draws on 139 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Osteoarthritis, arthritis, rheumatism, osteoarthrosis, myalgia : Plant part used: Root. Documented pharmacological profile: Indometacine-like.
   Selon Auteur (2018) : In the present study anti-inflammatory activity of ethanol extract of Petiveria alliacea whole plant were investigated. alliacea whole plant extract possess strong anti-inflammatory property. Selon GERMANO DHP (2003) : alliacea roots orally administered to rats showed an inhibitory effect on carrageenin & nystatin-induced paw oedema, and reduced the granuloma formation.
2. Candidiasis : Plant part used: Sheet. Documented pharmacological profile: Fluconazole-like.
   Selon Illnait-Zaragozí1 M (2014) : albicans and 15 Candida non-albicans) which showed resistance to fluconazole. The aim of the present work it was to evaluate the in vitro antifungal activity of crude hydro-alcoholic extract of Petiveria alliacea L (HAEPAL) versus fluconazole against Candida isolates. Selon Kim S (2006) : Antibacterial and antifungal activity of sulfur-containing compounds from Petiveria alliacea L.
3. Cancer : Plant part used: Sheet. Documented pharmacological profile: Doxorubicine-like.
   Selon HERNANDEZ JF (2017) : alliacea extract in tumor/non-tumorigenic cell lines and murine breast cancer model. Additionally, in vivo treatment of BALB/c mice transplanted with the murine breast cancer TS/A tumor showed that P. Selon Auteur (1990) : Three years later, they reported Anamu was directly cytotoxic to leukemia & lymphoma cancer cells but only inhibited the growth of breast cancer cells.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo from the Traditional Martinique Pharmacopoeia.