Plantago ovata (Yellow plantain) : medicinal properties in alcoholic extraction

Plantago ovata (Yellow plantain) — family Plantaginacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 66 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Gastric ulcer : Plant part used: Seed. Documented pharmacological profile: Ranitidine-like. Mentioned synergistic association: Cydonia oblonga, Ocimum basilicum, Plantago major- semences.
   Selon KHEDHER A (2022) : wt) significantly protected against ethanol-induced gastric ulcer in rats by decreasing the ulcer index value & preserving the integrity of the gastric mucosa. In conclusion, the POE protects against gastric ulcer due to its antioxidant potential & presence of bioactive molecules. Selon HARIS M (2025) : The results demonstrated that both PTD & HAE significantly reduced ulcer index, gastric volume, malondialdehyde, & myeloperoxidase levels (p<0.05), while enhancing superoxide dismutase 3, prostaglandin E2, & pH levels.
2. Dyspepsia, gastric ulcer : Plant part used: Sheet. Documented pharmacological profile: Omeprazole-like.
   Selon KHEDHER A (2022) : wt) significantly protected against ethanol-induced gastric ulcer in rats by decreasing the ulcer index value & preserving the integrity of the gastric mucosa. In conclusion, the POE protects against gastric ulcer due to its antioxidant potential & presence of bioactive molecules. Selon HARIS M (2025) : The results demonstrated that both PTD & HAE significantly reduced ulcer index, gastric volume, malondialdehyde, & myeloperoxidase levels (p<0.05), while enhancing superoxide dismutase 3, prostaglandin E2, & pH levels.
3. Obesity, metabolic syndrome : Plant part used: Sheet. Documented pharmacological profile: Orlistat(Tetrahydrolipstatin)-like.
   Selon GALISTEO M (2010) : The methyl-cellulose-supplemented diet reduced body weight, hyperlipidemia, circulating free fatty acids concentration & ameliorated adipose tissue secretion of adiponectin & TNF-alpha. Conclusions: The soluble dietary fibers essayed are more beneficial than insoluble fiber in the treatment of metabolic syndrome, being the soluble & fermentable the more efficient to improve metabolic alterations. Selon USATIUC LO (2025) : Polycystic ovary syndrome (PCOS), a common & multifactorial endocrine disorder in reproductive-aged women, is strongly associated with insulin resistance (IR) & type 2 diabetes mellitus (T2DM), & also affects up to one in four women with type 1 diabetes mellitus (T1DM).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Stan Shebs without modification. License : CC BY-SA 3.0.