Portulaca oleracea (Koupié) : medicinal properties in alcoholic extraction

Portulaca oleracea (Koupié) — family Portulacacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 28 indications in alcoholic extraction for this species. The monograph draws on 101 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Doxorubicine-like.
   Selon Baradaran VR (s.d.) : Furthermore, the extract as ethnobotanical may be used as adjunctive anti-cancer therapy against glioblastoma multiforme. Glioma is considered the most common primary brain tumor & its malignant form is the most lethal adult brain tumor, that glioblastoma covers about 50 % of glioma tumors. Selon Rahimi V (s.d.) : Furthermore, the extract as ethnobotanical may be used as adjunctive anti-cancer therapy against glioblastoma multiforme.
2. Respiratory disorders : Plant part used: Sheet. Documented pharmacological profile: Dexaméthasone-like.
   Selon Baradaran VR (2019) : Acute lung injury (ALI) & acute respiratory distress syndrome (ARDS) are classified as two lung complications arising from various conditions such as sepsis, trauma & lung inflammation. Taken together, our findings reveal that PO extract dose-dependently displays anti-oxidant & anti-inflammatory activity against LPS-induced rat ALI, paving the way for rational use of PO as a protective agent against lung-related inflammatory disease. Selon Jalali J (2022) : This indicates that purslane might have a potential role in the management of metabolic syndrome through different underlying mechanisms including antioxidant, anti-inflammatory, anti-hyperlipidemic, anti-obesity, & antidiabetic.
3. Pain, hyperalgesia : Plant part used: Aerial parts. Documented pharmacological profile: Diclofenac-like.
   Selon Chan K (2000) : Chan K et al, The analgesic & antiinflammatory effects of Portulaca oleracea L. Selon Jalali J (2023) : It has been shown that PO & its active constituents have considerable neurodegenerative, neuroprotective, & antinociceptive properties. Accordingly, our team classified & discussed the outcomes of some nervous system disorders comprising Alzheimer's disease, Parkinson's disease, depression, epilepsy, anxiety, psychosis, drug dependence, hypoxia, & pain; although, additional preclinical & clinical assessments are necessary to reinforce the beneficial effects of PO on nervous system disorders.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Robert Flogaus-Faust without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.