Ravenala madasgascariensis (The Traveller’s Tree) : medicinal properties in alcoholic extraction

Ravenala madasgascariensis (The Traveller’s Tree) — family Strelitziaceae.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 6 indications in alcoholic extraction for this species. The monograph draws on 20 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Gemcitabine-like.
   Selon Priyadarshini S (2020) : In the present study, the antitumor effect of successive ethanolic leaf extract over two human pancreatic cancer cell lines PANC1 & SW1990 was evaluated by MTT assay. Thus, the results validate the antitumor potential of RM leaf extract against pancreatic cancer a further study were aimed at the identification of active components responsible for the activity. Selon Sethuraman S (2020) : In the present study, the antitumor effect of successive ethanolic leaf extract over two human pancreatic cancer cell lines PANC1 & SW1990 was evaluated by MTT assay.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Acide ascorbique-like.
   Selon Priyadarshini S (2020) : Leaves of Ravenala madagascariensis have been traditionally used in the treatment of diabetes & was scientifically proven to be effective as an antidiabetic, hypolipidemic, renoprotective & antioxidant agent.
3. Type II diabetes mellitus : Plant part used: Sheet. Documented pharmacological profile: Glibenclamide-like.
   Selon Priyadarshini S (2019) : Conclusion: Thus, our results validate its traditional claim in the treatment of diabetes by stimulating the secretion of insulin, thereby suggesting a possible mechanism of its antidiabetic effect. The objective of this study was to establish the cytotoxicity profile & & to evaluate the insulin secretagogue effect of ethanolic root extract of Ravenala madagascariensis. Selon Priyadarsini R (2010) : The ethanolic and aqueous extracts showed a significant inhibitory effect on glucose diffusion in vitro and accordingly were screened at 200 and 400mg/kg, b.w for the in vivo antidiabetic activity on alloxan induced diabetic rats.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Phiro without modification (CC BY 4.0). License : CC BY 4.0.