Sorghum bicolor (Sorghum) : medicinal properties in alcoholic extraction

Sorghum bicolor (Sorghum) — family Poacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 164 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Sound. Documented pharmacological profile: Indometacine-like.
   Selon Bralley E (2008) : Hyaluronidase activity increases in chronic inflammatory conditions, e.g., inflammatory joint disease. Since hyaluronidase activity is important in conditions such as osteoarthritis & skin aging, these sorghum varieties deserve consideration for functional foods & beverages, & for nutraceutical & cosmeceutical ingredients. Selon Shim T (2013) : We investigated the toxicity & anti-inflammatory properties of a GGS extract.
2. Type II diabetes mellitus : Plant part used: Seed. Documented pharmacological profile: Acarbose-like.
   Selon Chung IM (s.d.) : Hwanggeumchal sorghum phenolic extracts in the streptozotocin-induced diabetic rats showed significant hypoglycemic activity for 14 days & significantly decreased the serum glucose, total cholesterol, triglycerides, urea, uric acid, creatinine, aspartate amino transferase & alanine amino transferase while it increased the serum insulin in diabetic rats but not in normal rats (p < 0.05) (at doses of 100 & 250 mg/kg for 14 days). Monech) in normal & streptozotocin-induced diabetic rats. Selon Nguyen PH (2014) : bicolor & its flavonoid-enrich extracts could be considered as supplemental & or functional foods having beneficial effects against blood coagulation-induced ischemia, possibly thromboembolism disease, as well as diabetes.
3. Oxidative stress : Plant part used: Shaft. Documented pharmacological profile: Acide ascorbique-like.
   Selon Vanamala JKP (2018) : Chronic diseases, such as cancers, are the top causes for morbidity & mortality in developed nations & are promoted by inflammation & oxidative stress. Moench), for their anti-inflammatory, antioxidant, anti-colon cancer, & immune modulator functions. Selon Khan I (2014) : Khan I et al, Acute effect of sorghum flour- containing pasta on plasma total polyphenols, antioxidant capacity & oxidative stress markers in healthy subjects: A randomised controlled trial.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Laurant Bonnal, CIRAD without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.