Syzygium malacense (Ponm Tayiti) : medicinal properties in alcoholic extraction

Syzygium malacense (Ponm Tayiti) — family Myrtacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The monograph draws on 73 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Amoxicilline-like, Tetracycline-like.
   Selon Sukandar EY (2020) : Antibacterial activity & combination extract with antibiotics were evaluated using agar diffusion method on Staphylococcus aureus, Bacillus subtilis, Escherichia coli, & Pseudomonas aeruginosa. The objectives of this study are to investigate antibacterial activity of 11 extracts from ten plants which were used in traditional medicine in Indonesia to treat infection disease & to evaluate interaction between potential antibacterial extract & antibiotics. Selon Quenon C (2022) : All compounds were tested against Staphylococcus aureus (18.75 < MIC < 75.0 µg/mL), Streptococcus pyogenes (2.34 < MIC < 18.75 µg/mL) and Pseudomonas aeruginosa (MIC = 150 µg/mL), & their structure–activity relationships were discussed.
2. Type II diabetes mellitus : Plant part used: Sheet. Documented pharmacological profile: Acarbose-like.
   Selon Bairy KL (2005) : Methods: The aqueous & alcoholic extracts were compared with glibenclamide for their influence on fasting blood sugar, lipid profile & liver glycogen in both normoglycemic & to streptozotocin induced (50mg/kg ip) hyperglycemic rats. In the hyperglycemic rats on chronic treatment both the extracts caused reduction in FBS & significantly reversed the diabetes induced hyperlipidemia and liver glycogen depletion. Selon Arumugam B (2014) : The presence of the potent antioxidant & antihyperglycemic agent myricitrin in the SM leaf extract indicates the potential use of the extract in the management of diabetes mellitus & its related complications.
3. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Acide ascorbique-like.
   Selon Batista AG (2020) : In this study, we supplemented a high-fat diet (HF) with 5% powder of freeze-dried Syzygium malaccense fruit (HS) & investigated proofs of peripheral insulin resistance, hippocampal AKT–GSK3-β–tau activation, learning /memory performance, & brain frontal lobe oxidative stress. The HS diet improved brain antioxidant enzyme activities. Selon Giovanna BA (2020) : In this study, we supplemented a high-fat diet (HF) with 5% powder of freeze-dried Syzygium malaccense fruit (HS) & investigated proofs of peripheral insulin resistance, hippocampal AKT-GSK3-beta-tau activation, learning/memory performance, & brain frontal lobe oxidative stress.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by PEAK99 without modification. License : CC BY 3.0.