Tecoma stans (Dandelion wood) : medicinal properties in alcoholic extraction

Tecoma stans (Dandelion wood) — family Bignoniacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 23 indications in alcoholic extraction for this species. The monograph draws on 41 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Viremia : Plant part used: Trunk. Documented pharmacological profile: Ribavirine-like.
   Selon Cardoso-Reis AC (2020) : The antiviral activity was assayed in vitro against the Zika virus by the MTT colorimetric method (n = 3). In the present study, ethanolic extracts from trunks & leaves of Tecoma species were tested in vitro using assays against the Zika virus. Selon Al-Azzawi A (2022) : This rapid and efficient method using flash chromatography was used for the isolation & purification of an isolated component A-3 that showed both antioxidant & antifungal activities.
2. Fungal infection : Plant part used: Sheet. Documented pharmacological profile: Itraconazole-like, Miconazole-like, Nystatine-like.
   Selon Al-Azzawi A (2022) : Component A-3 showed antioxidant activity using the DPPH & ABTS methods; antifungal activities when tested against Candida albicans; & more than 80% inhibitions in the third dilution when compared to itraconazole & nystatin as positive controls. This rapid and efficient method using flash chromatography was used for the isolation & purification of an isolated component A-3 that showed both antioxidant & antifungal activities. Selon Patriota LLS (2014) : Antifungal activity was evaluated by determining the minimal inhibitory (MIC) & fungicide (MFC) concentrations using fungal cultures containing only yeast form or both yeast & hyphal forms.
3. Cancer : Plant part used: Trunk.
   Selon Thirumal M (2013) : The current study, evaluate Invitro Antiproliferative activity of ethanolic crude extract of root (ERETS), stem bark(ESETS) & flowers(EFETS) of Tecoma stans against Human Breast Cancer Cell lines (MCF-7) at different concentrations using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT) assay. Root, stem bark & flowers extracts showed significant antiproliferative activity in dose dependable manner on the cell lines (MCF-7) but maximum activity was found to be with ethanolic extract of stem bark of T stans (ESETS). Selon Anburaj G (2016) : The human breast cancer cell line (Michigan Cancer Foundation-7 (MCF 7)) was obtained from National Centre for Cell Science (NCCS), Pune & grown in Eagles Minimum Essential Medium (EMEM) containing 10% fetal bovine serum (FBS).

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Laurel Toxico without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.