Antigonon leptoptus (Midjé-wôz) : medicinal properties in alcoholic extraction

Antigonon leptoptus (Midjé-wôz) — family Polygonacées`.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The monograph draws on 31 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Muscle contraction, spasm : Plant part used: Sheet. Documented pharmacological profile: Diazépam-like.
   According to Ranjan P (2015): Both the analgesic & muscle relaxant activity of the ethanolic extract of AL leaves at doses levels of 50, 100, 150, 200 & 250 mg/kg p.o. The objective of the present study is to investigate the analgesic & muscle relaxant activities of ethanolic extract of leaves of Antigonon leptopus (EEAL) in Albino rat by different pharmacological techniques.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Propylgalate-like.
   According to Elhaj AM (2015): The ethanol extract of AL (leaves) was screened for detect their free radical scavenging properties using 2.2Di (4-tert-octylphenyl)-1-picryl-hydrazyl (DPPH), while propyl galate was used as a standard antioxidant & screened for their cytotoxicity using 3-(4, 5-dimethyl thiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT). The tested antioxidant activity gave (89 ± 0.04 RSA%) in comparison to the control of propylgalate levels (72 ± 0.01RSA%), Primary phytochemical screening on leaves of AL appeared the rich of alkaloids, saponins, tannins, unsaturated sterol and/or triterpenes, flavonoids, glycosides & coumarins. According to Kavatagimath SA (2020): Ethanolic extract of AL flower was screened for antioxidant activity by DPPH method & its effects on blood glucose levels (OGTT, acute & sub-acute study) in Alloxan induced diabetic rats, effects on serum lipid profiles & histopathological study of pancreas.
3. Bacterial infection : Plant part used: Flower. Documented pharmacological profile: Streptomycine-like.
   According to Battu G (2009): The extracts showed significant antibacterial & antifungal activity against all the microorganisms tested & the effect so produced was compared with the standard drugs penicillin & nystatin. AL investigated for its preliminary phytochemical & antimicrobial activity. According to Govindasamy B (2014): Antibacterial activity was evaluated against fish & clinical pathogens.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Meneerke Bloem without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.