Chamaesyce hirta (Malonmen) : medicinal properties in alcoholic extraction

Chamaesyce hirta (Malonmen) — family Euphorbiacées.

Recognised external sources linked to this monograph: TRAMIL and French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 29 indications in alcoholic extraction for this species. The monograph draws on 75 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Amoxicilline-like, Gentamycine-like, Chloramphenicol-like, Vancomycine-like.
   According to Ogbulie JN (2007): The agar diffusion method was used to determine the antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and Bacillus subtilis at different concentrations while toxicological studies was carried out through intraperitoneal injection of albino rat with varying concentrations of the extract. typhi was not affected. According to Ogueke CC (2007): The agar diffusion method was used to determine the antibacterial activity on Staphylococcus aureus, E coli, Pseudomonas aeruginosa, Salmonella typhi and Bacillus subtilis at different concentrations while it was tested for toxicity on albino rats by injecting varying concentrations of the extracts through the intraperitoneal route.
2. Cancer : Plant part used: Whole plant.
   According to ANITHA P (2014): Ethanolic leaf extract of Euphorbia hirta was tested for its cytotoxicity against Dalton Lymphoma Ascites (DLA) and Ehrlich Ascites Carcinoma (EAC) cell lines using preliminary screening technique (Trypan Blue method and standard MTT colorimetric method). In the present study, in vitro anticancer effects of Euphorbia hirta were investigated. According to Sidambaram RR (2011): The extract showed dose dependent antitumor activity.
3. Acne : Plant part used: Root. Documented pharmacological profile: Clindamycine-like.
   According to Kumar GS (2007): Propionibacterium acnes & Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. The MIC values were the same (0.049 mg/ml) for both bacterial species and the MBC values were 0.049 & 0.165 mg/ml against Propionibacterium acnes and Staphylococcus epidermidis, respectively. According to Ogbulie JN (2007): The agar diffusion method was used to determine the antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and Bacillus subtilis at different concentrations while toxicological studies was carried out through intraperitoneal injection of albino rat with varying concentrations of the extract.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Harry Rose from South West Rocks, Australia without modification (CC BY 4.0). License : CC BY 4.0.