Oryza sativa (Diri) : medicinal properties in alcoholic extraction

Oryza sativa (Diri) — family Poacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 14 indications in alcoholic extraction for this species. The monograph draws on 91 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sound. Documented pharmacological profile: Doxorubicine-like.
   Selon Duansak N (2022) : Rice bran has antioxidant & cardioprotective properties, and can act as a food supplement with potential health benefits, such as lowering blood pressure, hepatic steatosis, & inflammation. Male Institute of Cancer Research mice were fed with a high-fat diet (HFD) for 8 weeks & then supplemented with 220 & 1,100 mg/kg/d RBE while the low-fat diet group (control) were not. Selon Perez-Ternero C (2017) : Liver steatosis was reduced by RBEE supplementation of LFD (1% RBEE) and HFD (1 & 5% RBEE) & nuclear peroxisome proliferator-activated receptor-α expression upregulated in the HDF 5% RBEE group.
2. Psoriasis : Plant part used: Seed. Documented pharmacological profile: Dexamethasone-like.
   Selon Ampawong S (2020) : The results showed that the rice extract reduced the severity of psoriasis by decreasing the epidermal thickness, acanthosis, hyperkeratosis, epidermal inflammation & degree of apoptosis induction via caspase-3, increasing the expression levels of anti-inflammatory cytokines (IL-10 & TGF-β), (3) reducing the levels of pro-inflammatory cytokines (IL-6, IL-8, IL-20, IL-22 & TNF-α), chemokines (CCL-20) & anti-microbial peptides (psoriasin & β-defensin), (4) enhancing the antioxidative property (Nrf-2), (5) downregulating the levels of psoriasis-associated genes (psoriasin, β-defensin, koebnerisin.15L & koebnerisin 15S) & (6) upregulating the levels of psoriasis-improving genes (caspase-14, involucrin & filaggrin). Psoriasis-related genes, cytokines & chemokines were examined; in addition, the antioxidative & anti-inflammatory properties & the immuno-histo-pathological features of this condition were studied. Selon Auteur (2016) : SHANMUGASUNDARAM EC, ANTI-INFLAMMATORY EFFECT OF AQUEOUS EXTRACT OF LEAVES OF Oryza sativa Linn IN IN-VITRO ENZYME ASSAYS & CARAGEENAN INDUCED PAW EDEMA IN WISTAR RATS, Dissertation, JKKN College of Pharm 2016-.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Seed. Documented pharmacological profile: Diclofénac-like.
   Selon Ashraf S (2019) : The present study is based on extraction of oil from super kernel basmati rice which has shown effective analgesic, anti- inflammatory, & anti-arthiritic activities. Selon Auteur (2016) : SHANMUGASUNDARAM EC, ANTI-INFLAMMATORY EFFECT OF AQUEOUS EXTRACT OF LEAVES OF Oryza sativa Linn IN IN-VITRO ENZYME ASSAYS & CARAGEENAN INDUCED PAW EDEMA IN WISTAR RATS, Dissertation, JKKN College of Pharm 2016-.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vyacheslav Argenberg without modification (CC BY 4.0). License : CC BY 4.0.