Blighia sapida (Aki) : vertus médicinales en extraction alcoolique

Blighia sapida (Aki) — famille Sapindacées.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. La monographie s’appuie sur 55 références scientifiques enregistrées pour l’espèce.

Indications thérapeutiques en extraction alcoolique :

Note : les extraits de références scientifiques sont conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction, afin de respecter le texte source des publications.

1. Arthrose, arthrite, rhumatisme, oedème : Partie usitée : ecorce de tige. Profil pharmacologique documenté : Diclofénac-like.
   Selon Sinmisola A (2019) : Traditionally it is used to manage numerous ailments like backache, constipation, cancer, fever in young children, gonorrhea, dysentery, psychosis, hernia, stomach ache, malaria, rheumatism, typhoid etc. This review summarizes its phytochemistry, nutritional properties, ethnobotany & pharmacology. Selon Yiadom KA (2018) : n this study, the medicinal capabilities of Blighia sapida seeds are investigated by evaluating the antioxidant & antiproliferative activities on, lung, prostate, skin, leukemic cancers & normal liver cells using methods such as GC-MS, MTT & Resazurin based cell viability assays & DPPH/FRAP assays.
2. Plasmodiase : Partie usitée : ecorce de tige. Profil pharmacologique documenté : Coartem-like.
   Selon Sinmisola A (2019) : This review summarizes its phytochemistry, nutritional properties, ethnobotany & pharmacology. They are used in the management of diverse disease conditions such as diarrhoea, conjunctivitis, fever, internal hemorrhage, dysentery, cutaneous skin infections & bacterial infections amongst others. Selon Yiadom KA (2018) : n this study, the medicinal capabilities of Blighia sapida seeds are investigated by evaluating the antioxidant & antiproliferative activities on, lung, prostate, skin, leukemic cancers & normal liver cells using methods such as GC-MS, MTT & Resazurin based cell viability assays & DPPH/FRAP assays.
3. Diabète mellitus de type II : Partie usitée : ecorce de tige. Profil pharmacologique documenté : Glibenclamide-like.
   Selon OJO OA (2017) : The significant increase in the lipid peroxidation (malonaldehyde), homeostasis model assessment-insulin resistance scores (HOMA-IR) & decrease in serum insulin, pancreatic β-cell scores as well as antioxidant marker enzymes in untreated diabetic rats compared to normal control rats were reversed by the BS stem bark ethanol extract & Glibenclamide. Methods: Diabetes was induced by intraperitoneal injection of alloxan (65 mg/kg body weight) for 21 days, and orally administered with Glibenclamide (5 mg/kg body weight), 50–150 mg/kg body weight of B. Selon OLOYEDE OB (2014) : Thus the antidiabetic activity of methanolic Blighia sapida leaf extract & its capability to halt oxidative stress & dyslipidemia in alloxan-induced diabetic rats were investigated.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et le détail des références scientifiques sont disponibles dans la fiche monographique complète.

Crédit photo : Photo de Michael Hermann sans modification (CC BY 4.0). Licence : CC BY 4.0.