Citrus sinensis (Zoranj) : vertus médicinales en extraction alcoolique

Citrus sinensis (Zoranj) — famille Rutacées.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 12 indications en extraction alcoolique pour cette espèce. La monographie s’appuie sur 55 références scientifiques enregistrées pour l’espèce.

Indications thérapeutiques en extraction alcoolique :

Note : les extraits de références scientifiques sont conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction, afin de respecter le texte source des publications.

1. Infection bacterienne : Partie usitée : Feuille. Profil pharmacologique documenté : Ciprofloxacine-like.
   Selon Omodamiro OD (2013) : Extracts of both peels & leaves showed moderate antibacterial activity against Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Proteus mirabilis & Pseudomonas aeruginosa. The objectives of this study were to evaluate the antioxidant, anti-inflammatory & antibacterial properties of ethanolic extracts of Citrus sinensis peels & leaves. Selon Punitha V (2022) : The antimicrobial activities & minimum inhibitory concentrations (MIC) & minimum bactericidal/fungicidal concentration (MBC/MFC) values were determined using the agar well diffusion & micro dilution method respectively against Gram-positive bacteria (Staphylococcus aureus & Staphylococcus epidermis), Gram-negative bacteria (Pseudomonas aeruginosa & Klebsiella pneumoniae), as well fungi (Candida albicans & Aspergillus niger).
2. État inflammatoire : Partie usitée : Fruit. Profil pharmacologique documenté : Aspirine-like.
   Selon Auteur (2017) : Furthermore, CB, cilantro, & spikenard EOs primarily inhibited protein molecules related to inflammation, immune responses, & tissue-remodeling processes, suggesting they have anti-inflammatory & wound healing properties. All the studied oils were significantly anti-proliferative against these cells. Selon DURMUS N (2024) : Citrus peels are rich in bioactive phenolic compounds with various health effects including antioxidant, antiobesity, antiinflammatory, antihypertensive, anti-hypercholesterolemic, antimicrobial, antidiabetic, & anticarcinogenic activities.
3. Stress oxydatif : Partie usitée : Fruit. Profil pharmacologique documenté : Acide ascorbique-like.
   Selon FAN C (2023) : The results indicated that the NOB significantly ameliorated lipid deposition, oxidative stress, & inflammation in NAFLD in both models. Nobiletin (NOB), a flavonoid with significant antioxidant potential, holds promise for treating nonalcoholic fatty liver disease (NAFLD). Selon LUO J (2025) : Compared to traditional solvent extraction, this process exhibited the following advantages: (1) qualitative analysis by ultra-performance liquid chromatography-quadrupole-Orbitrap high-resolution mass spectrometry identified seven additional flavonoids in the two-step extract, revealing that SCE was primarily composed of low-polarity flavonoids, and REE was primarily composed of high-polarity flavonoids; (2) quantitative analysis by HPLC demonstrated that the two-step extraction significantly enhanced flavonoid content, with total flavonoids increasing by 11.75% and polymethoxyflavones rising by 19.55%; (3) antioxidant & antimicrobial analyses revealed the potent antioxidant capacity of REE extracts and the superior antimicrobial activity of SCE extracts.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et le détail des références scientifiques sont disponibles dans la fiche monographique complète.

Crédit photo : Photo de Ellen Levy Finch sans modification (CC BY-SA 3.0). Licence : CC BY-SA 3.0.