Abelmoschus esculentus (Gonbo) : medicinal properties in alcoholic extraction

Abelmoschus esculentus (Gonbo) — family Malvacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 11 indications in alcoholic extraction for this species. The monograph draws on 162 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Gastric ulcer : Plant part used: Fruit. Documented pharmacological profile: Oméprazole-like.
   According to Ortaç D (2018): Discussion & conclusions: Our in vivo data indicate that okra has a gastroprotective effect against ethanol & could reduce the gastric ulcer as seen from biochemical & histopathological results. Objective: In the present study, we evaluated the gastroprotective effect of okra against ethanol-induced acute gastric mucosal injury in animal models. According to Yasin H (2020): This research aims to examine the anti-inflammatory & anti-ulcer attributes of AE extract against gastric lesions.
2. Infection in farmed Dicentrarchus labrax : Plant part used: Seed.
   According to Guebebia S (2023): Moreover, at mid-stage maturity, AE fruit extracts exhibited a major antibacterial effect against Vibrio anguillarum. Methods: This study examined the modifications in total phenolic content (TPC), total flavonoid content (TFC), & antioxidant & antibacterial capacities of three AE fruit hydroalcoholic extracts during three comestible maturity stages. According to Devanesan S (2021): Conclusion: Compared to other NPs the NPs synthesized in this study were smaller in size & exhibited a higher level of antibacterial activity, cytotoxicity & apoptosis at minimal concentrations, & this is the first study on okra flower-induced anticancer & antimicrobial activities,.
3. – liver disorders : Plant part used: Fruit. Documented pharmacological profile: Silymarine-like.
   According to Wahyuningsih SP (2021): Therefore, this study aims to determine the antioxidant & hepatoprotective potential of red okra fruit ethanol extract against NaNO2-induced liver damage. Besides, the oxidants (malondialdehyde, F2-isoprostanes, & nitric oxide) in the liver homogenate significantly decreased in the P4 group, which were given red okra ethanol extract (p < 0.05). According to Sunilson JA (n.d.): The oral administration of the extract (250 & 500 mg/kg body weight), significantly reduce CCl4 induced hepatotoxicity in rats, as judged from the serum & tissue activity of marker enzymes [Glutamate oxaloacetate transaminase (GOT), Glutamate pyruvate transaminase (GPT) & alkaline phosphatase (ALP)].

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

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