Acacia nilotica (Akasia-Kayenn’) : medicinal properties in alcoholic extraction

Acacia nilotica (Akasia-Kayenn’) — family Mimosacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 9 indications in alcoholic extraction for this species. The monograph draws on 53 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: root. Documented pharmacological profile: Recophine-like, Pefloxacine-like.
   According to Okoro SO (2014): The extract fractions generally exhibited marked antibacterial activities on Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus vulgaris, Salmonella typhi, Shigella dysenteriae Staphylococcus aureus & Escherichia coli except on Streptococcus pneumoniae & Streptococcus pyogenes. In-vitro agar-diffusion sensitivity tests of crude extract fractions of the plant extracts using ethanol, chloroform, methanol, petroleum ether, water & ethyl acetate were investigated on nine bacterial isolates. According to Elamary RB (2020): Escherichia coli is by far the most prevalent causative agent with the percentage of 73.7% followed by Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, & Acinetobacter baumannii.
2. Dental plaque, periodontitis, tooth decay : Plant part used: Sheet. Documented pharmacological profile: Chlorhexidine-like. Mentioned synergistic association: Eucalyptus sp, association synergique avec MURRAYA KOENIGII-(L)-Spreng (Feuille), Psidium guajava-feuilles.
   According to Fadh il Y (2021): The study suggests that water leaves extract of “Babool"can be used as an alternative strategy for treatment of dental pulp through chondrogenic differentiation. According to Kabbashi AS (2016): Human parasitic infections still represent a challenging public health problem worldwide, especially in tropical & subtropical regions.
3. Giardiasis : Plant part used: TRUNK. Documented pharmacological profile: Métronidazole-like.
   According to Kabbashi AS (2016): Giardiasis is the most common cause of parasitic gastro-intestinal disease and up to two hundred million people are chronically infected with Giardia lamblia globally with 500,000 new cases reported annually. Method: The ethanolic extract of AN bark, with different concentrations (500, 250 & 125 ppm) were investigated together with Metronidazole as a reference control at 312.5 μg/ml against Giardia lamblia trophozoites.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo de Varinder Naturaphile sans modification (CC BY-SA 4.0). License : CC BY-SA 4.0.