Acalypha indica (Ti-kodenn) : medicinal properties in alcoholic extraction

Acalypha indica (Ti-kodenn) — family Euphorbiacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 26 indications in alcoholic extraction for this species. The monograph draws on 58 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Erythromycine-like.
   According to Tilak AH (2015): Butanol, ethanol & methanol leaf extract of A indica & A lebbeck were tested for antibacterial activity by disc diffusion technique & broth dilution method (MIC & MBC) against Pseudomonas aeruginosa, a gram negative, aerobic Rod found commonly in soil & water. All the extracts exhibited antibacterial activity against the tested bacterial strain. According to MOHAN CS (2012): The ethanol extract of leaves was found to be exhibit activity against Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa & Staphylococcus aureus.
2. Cancer : Plant part used: whole plant. Documented pharmacological profile: Cisplatine-like.
   According to Leong KX (2022): Both F1 & quercetin inhibited the proliferation of MDA-MB-231 cells in different ways, but F1 is likely a better potential anticancer agent derived from the green approach towards breast cancer treatment.,:. According to Sanseera D (2012): The methanol extract showed anticancer activity against NCI- H187-Small Cell Lung Cancer with an IC50 of 25.00 μgmL-1. (Aerial parts) were investigated for antioxidant activity, anticancer activity, & cytotoxicity.
3. Helminthiasis : Plant part used: root. Documented pharmacological profile: Albendazole-like.
   According to RANJU Garai (2011): Ethanol extract from the Acalypha indica leaves of investigated for their anthelmintic activity against Pheretima posthuma. According to -CHENGAIAH B (2009): The aim of present study was to evaluate anthelmintic potential of crude alcoholic extract of root of A indica using Pheretima posthuma as test worm. Albendazole (10 mg/ml) was included as standard reference & distilled water as control.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo de J.M. Garg sans modification (CC BY 3.0). License : CC BY 3.0.