Adenium obesum (Desert Rose) : medicinal properties in alcoholic extraction

Adenium obesum (Desert Rose) — family Apocynacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 5 indications in alcoholic extraction for this species. The monograph draws on 34 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet.
   According to Alsherhri A (2022): In addition, we also evaluated the anticancer activity of AOE, & it was observed that AOE was found to be cytotoxic against A549 lung cancer cells. It was found that AOE inhibited the viability of A549 lung cancer cells by inducing nuclear condensation & fragmentation. According to Hoffman JJ (1977): An ethanol extract of Adenium obesum exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx test system.
2. Oxidative stress : Plant part used: Sheet. Documented pharmacological profile: Acide ascorbique-like.
   According to Kershi RM (2014): Also, there is a good correlations between antioxidant activity (R2 = 0.9368) for water/ethanol series extracts.,. The extracts were analyzed for monomeric anthocyanins contents & antioxidant activities. According to Ebrahim N (2013): Also, there is a good correlation between antioxidant activity (R2 = 0.9368) for water/ethanol series extracts,.
3. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Sheet.
   According to Alsherhri A (2022): In this report, the antioxidant, anti-inflammatory, & anticancer activities of ethanolic leaf extract from A. Furthermore, ethanolic AOE demonstrated the anti-inflammatory potential of AOE in murine alveolar macrophages (J774A.1) as an in vitro model system. According to Alsherhri A (2022): In this report, the antioxidant, anti-inflammatory, and anticancer activities of ethanolic leaf extract from A.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Steve without modification (CC0 1.0). License : CC0 1.0.