Alstonia scholaris (Pali mari) : medicinal properties in alcoholic extraction

Alstonia scholaris (Pali mari) — family Apocynacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The monograph draws on 131 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Psychiatric disorders, schizophrenia : Plant part used: Sheet. Documented pharmacological profile: Halopéridol-like. Mentioned synergistic association: association synergique avec BACOPA MONNIERI-(L)-Pennel (Plante entiere).
   According to JASH R (2014): Treatment of Psychiatric diseases like schizophrenia is largely palliative & more Importantly, a prominent adverse effect prevails with the majority of antipsychotic drugs, which are the extrapyramidal motor disorders. The results largely pointed out the fact that both the extract may be having the property to alleviate the positive symptoms of schizophrenia by reducing the dopamine levels of dopaminergic neurons of the brain.
2. Helminthiasis : Plant part used: LEAVES AND STEM BARK. Documented pharmacological profile: Albendazole-like.
   According to Singh S (2013): stem bark & roots were investigated for the anthelmintic activity against Pheretima posthuma. Albendazole (20 mg/ml) was used as reference standard while normal saline served as a control.
3. Female contraception : Plant part used: Sheet. Documented pharmacological profile: 17α-Ethynil estradiol-like.
   According to Chaudhary M (2017): For estrogenic/antiestrogenic activity, ovariectomized female rats were administered with the HAAS alone as well as with 17α-Ethynil estradiol (EE) (1 μ/rat/day) for 7 consecutive days. (HAAS) in female rats.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by D Neethidoss without modification (CC BY 2.0). License : CC BY 2.0.