Annona squamosa (Apple and Cinnamon) : medicinal properties in alcoholic extraction

Annona squamosa (Apple and Cinnamon) — family Annonacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 31 indications in alcoholic extraction for this species. The monograph draws on 181 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Campothécine like.
   According to MEHTA SD (2017): Traditionally, Annona Squamosa Linn has been used for treatment of cancer, diabetes, microbial infection, cardiac disease, jaundice and other liver related disorder. Aim of the study: The main objective of study is to evaluate hepatoprotective activity of the hydroalcoholic extract of seeds of AS using the carbon tetrachloride induced liver toxicity in rats. According to Chen Y (2012): These compounds all exhibited significant cytotoxic activity in vitro against five human tumor cell lines.
2. Arthritis, osteoarthritis, rheumatism, oedema : Plant part used: Root. Documented pharmacological profile: Diclofenac-like.
   According to Hemalatha K (2009): An attempt was made to prepare the alcoholic & aqueous extracts of root of Annona squamosa were subjected for chemical analysis & anti-inflammatory (carrageenan induced rat paw edema model method) activity. The results of anti-inflammatory studies at the doses 200 & 400 mg/kg b. According to SINGH DP (2012): The anti-inflammatory activity was evaluated by using Plethysmometer.
3. Psoriasis : Plant part used: Sheet. Mentioned synergistic association: formulation traditionnelle avec Curcuma longa-rhizome.
   According to Kawjit Natapong (2014): (rhizome), Curcuma longa L. (rhizome) & Annona squamosa L. According to Saelee C (2011): Psoriasis is a chronic inflammatory skin disorder characterized by rapid proliferation of keratinocytes & incomplete keratinization.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Adityamadhav83 without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.