Bacopa monnieri (Ti-veronik) : medicinal properties in alcoholic extraction

Bacopa monnieri (Ti-veronik) — family Scrofulariacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 24 indications in alcoholic extraction for this species. The monograph draws on 124 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Heart conditions : Plant part used: Whole plant. Documented pharmacological profile: Quinidine-like.
   According to Rashid S (1990): Rashid S et al Cardiovascular effects of Bacopa monnieri (L.) Pennel extract in Rabbits. According to Stough CK (2012): A randomized controlled trial investigating the effect of Pycnogenol & Bacopa CDRI08 herbal medicines on cognitive, cardiovascular & Biochemical functioning in cognitively healthy elderly people: The Australian Res Council Longevity Intervention Study Protocol.
2. Parkinson's disease : Plant part used: Whole plant. Documented pharmacological profile: Levodopa-like. Mentioned synergistic association: association synergique avec MUCUNA PRURIENS-(L)-DC (Semence).
   According to Gunduluru Swathi (2014): Parkinson’s disease (PD) is the second most neurodegenerative disorder. The BM may provide a Platform for future drug discoveries & novel treatment strategies in PD & can act as Antiparkinsonian agent. According to Kiani AK (2020): Neurological disorders like Parkinson disease & Alzheimer disease, spinal cord injury & stroke have some recurrent characteristics such as abnormal protein aggregation, oxidative stress induction, apoptosis, excitotoxicity, perturbation of intracellular Ca2+ homeostasis & inflammation.
3. Convulsion, epilepsy : Plant part used: Sheet. Documented pharmacological profile: Diazepam-like.
   According to Kaushik Darpan (2009): The ethanolic extract of leaves produced significant anticonvulsant activity for all the different models studied. The ethanolic extract of Bacopa monniera was tested for anticonvulsant activity in albino rats, using different convulsive models. According to Paulose CS (2008): Paulose CS et al, Neuroprotective rôle of Bacopa monnieri Extract in epilepsy & Effect of glucose supplementation during hypoxia: glutamate Receptor gene Expression.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Vengolis without modification (CC BY-SA 3.0). License : CC BY-SA 3.0.