Calotropis procera (Bwa-laswa) : medicinal properties in alcoholic extraction

Calotropis procera (Bwa-laswa) — family Asclépiadacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 20 indications in alcoholic extraction for this species. The monograph draws on 122 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: 5-Fluoro-Uracile-like, Fluoro-Uracile-like.
   According to Arul B (2004): (ECP) has been evaluated against Dalton's ascitic Lymphoma (DAL) in Swiss albino mice. The antitumor activity of the ethanolic extract of Calotropis procera R. According to BHAGAT M (2010): Results revealed that the extracts of the plant possessed in vitro anticancer potential against HCT-15 (colon) cancer cell line at different concentrations.
2. Osteoarthritis, rheumatoid arthritis, oedema, rheumatism : Plant part used: Root. Documented pharmacological profile: Dexaméthasone-like, Ibuprofene-like.
   According to Author (2022): procera possesses anti-inflammatory, antibacterial, antipyretic, antidiabetic, anticancer & antioxidant properties. procera, it has been used in traditional medicine as a purgative, antihelmintic as well as in the treatment of leucoderma, ulcer, rheumatoid arthritis & diseases of the spleen, liver & stomach. According to Parihar G (2011): The experimental paradigms used were Complete Freund’s Adjuvant (CFA) induced arthritis (chronic inflammation), acetic acid induced vascular permeability model in mice for anti-inflammatory activity.
3. Osteoarthritis, arthritis, oedema, rheumatism : Plant part used: Sheet. Documented pharmacological profile: Indometacine-like.
   According to Parihar G (2011): The experimental paradigms used were Complete Freund’s Adjuvant (CFA) induced arthritis (chronic inflammation), acetic acid induced vascular permeability model in mice for anti-inflammatory activity. Thus, the present study revealed that the ethanol extract of C procera exhibited significant anti-inflammatory activity in the tested models. According to Singh H (2000): Inflammation induced by latex of Calotropis procera—a new model to evaluate anti-inflammatory drugs.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Wilrooij without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.