Ceiba pentandra (Fromajié) : medicinal properties in alcoholic extraction

Ceiba pentandra (Fromajié) — family Bombacacées.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 19 indications in alcoholic extraction for this species. The monograph draws on 64 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Bacterial infection : Plant part used: Sheet. Documented pharmacological profile: Chloramphénicol-like.
   According to Author (2017): In the present study the aqueous, methanol, ethanol & acetone extract of Ceiba pentandra were screened for the presence of phytochemical components and tested for antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterobacter aérogènes, Pseudomonas a aeruginosa, Salmonella Typhimurium, Salmonella typhi, Staphylococcus epidermidis & Proteus vulgaris. The acetone extracts had wide range of antibacterial activity against bacterial pathogens than the ethanol & methanol extract, whereas aqueous extract was slightly higher antibacterial activity as ethanol extract. According to Muñoz-Cazares N (2018): pentandra against QSS-regulated phenotypes of Chromobacterium violaceum & Pseudomonas aeruginosa.
2. Type II diabetes mellitus : Plant part used: Bark. Documented pharmacological profile: Metformine-like. Mentioned synergistic association: AMARANTHUS VIRIDIS.
   According to Manoharan S (2009): Diabetes mellitus was induced with streptozotocin & graded doses of the ethanolic bark extract (200 & 400 mg/kg, b.w.) were then administered to the experimentally diabetic rats. Objective: To evaluate the hypoglycaemic & anti-hyperglycaemic effect of ethanolic extract of CP bark in normal & streptozotocin induced diabetic rats. According to Djomeni PDD (2006): The results of this experimental animal study indicated that C pentandra possesses antidiabetic activity; & thus is capable of ameliorating hyperglycaemia in streptozotocin-induced type-2 diabetic rats & is a potential source for isolation of new orally active agent(s) for anti-diabetic therapy,.
3. Dermatomycosis : Plant part used: Sheet. Documented pharmacological profile: Ketoconazole-like.
   According to Chekuboyina RK (2012): aeruginosa) & fungal stains, more specifically Aspergillus flavans, Aspergillus niger, Candida albicans & Saccharomyces cerevisiae. Maximum activity was observed on bacterial strains compared with fungal strains. According to KWACHUKWU IN (2008): Results showed that all the extracts inhibited the growth of standard & local strains of the organisms used, namely Epidermophyton floccosum, Microsporum canis, Trichophyton rubrum & Candida albicans.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by FBenjr123 without modification (CC BY 4.0). License : CC BY 4.0.