Cicurbita pepo (Courgette) : medicinal properties in alcoholic extraction

Cicurbita pepo (Courgette) — family Cucurbitacées.

Recognised external sources linked to this monograph: French Pharmacopoeia.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 7 indications in alcoholic extraction for this species. The monograph draws on 60 scientific references recorded for the species.

Therapeutic indications in alcoholic extraction:

Note: scientific reference excerpts are kept in their original language (most often English), without translation, to respect the source text of publications.

1. Cancer : Plant part used: Sheet. Documented pharmacological profile: Taxus baccata-like, CISPLATINE-like.
   According to Shokrzadeh M (2010): nigrum extract was significantly higher than the extract of Taxus baccata & Cisplatin, herbal & chemical control positive anticancer compounds, respectively, on all four cell lines (P < 0.05). nigrum was studied on normal [Chinese hamster ovarian cells (CHO) & rat fibroblast] & cancer (HepG2 & CT26) cell lines. According to Makni M (2008): Hypolipidemic & hepatoprotective effects of flax & pumpkin seed mixture rich in ω-3 & ω-6 fatty acids in hypercholesterolemic rats.
2. Osteoarthritis, arthritis, rheumatism, oedema : Plant part used: Fruit.
   According to Agrawal K (2022): Several studies describes the medicinal properties such as anti-diabetic, cardioprotective, anti- depressive, antioxidant, anti-carcinogenic, anti-inflammatory of Pumkin seeds & seed oil. According to Das ML (2015): oleifera is very important for medicinal value such as Hepatoprotective, anti-inflammatory, hysteria, lower of serum cholesterol, phospholipid, Triglyceride etc.
3. Wound, incision, injury : Plant part used: Fruit.
   According to Bardaa S (2016): High content of these bioactive components were in agreement with an efficient wound healing by the mean of an in vivo study. Methods :The composition & content of certain bioactive constituents of the cold pressed oil obtained from CP seeds were analyzed & studied for their wound healing properties. According to Almohaimeed HM (2022): (CP) ethanolic extract in prompting excisional wound healing in rats exposed to chronic stress, & to explain how it works.

Further indications (including other extraction modes where applicable), dosages, precautions for use and full scientific references are available in the complete monograph.

Photo credit : Photo by Silar trouvé without modification (CC BY-SA 4.0). License : CC BY-SA 4.0.